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Hot Spot & Itch Relief Medicated Spray

Size: 8 oz

Give hot spots and itchy, irritated skin targeted care right where your pet needs it. This easy-to-use medicated spray helps soothe itching and discomfort while calming and nourishing the skin, no full bath required.

How to use

Spray affected area thoroughly and evenly until wet. Do not allow pet to lick product. Continue to supervise pet until coat and skin are completely dry. Apply twice daily for one week, then once per day for one more week. If needed, continue every other day for two additional weeks. For dogs and cats 12 weeks and over.

Ingredients
Active Ingredients: Lidocaine: 0.5% Hydrocortisone: 0.2% Benzethonium Chloride: 0.1% Inert Ingredients: Purified Water, Glycerin, Polysorbate-20, Allantoin, Lactic Acid, Wheat Germ Oil, Fragrance, Preservative.
Dalmatian dog with Veterinary Formula Hot Spot & Itch Relief Medicated Spray on grass

What Sets Apart Veterinary Formula

Other Brands
Hot Spots

Helps soothe hot spots and skin irritations

Included
Not included
Soothes Skin

Soothes skin discomfort including itching and irritation with lidocaine and oatmeal

Included
Not included
Gentle Cleanse

Cleanses gently while promoting skin comfort

Included
Not included
Fast-Acting

Fast-acting formula may provide noticeable improvement quickly

Included
Not included
Accessibly Priced

Vet-recommended care you can trust, at an accessible price

Included
Not included
Easy-to-Use Spray

Convenient spray for mess-free, direct application

Included
Not included
  • Trusted by pet parents nationwide
  • 150K+ positive reviews
  • 18+ years of pet health expertise
  • Trusted by pet parents nationwide
  • 150K+ positive reviews
  • 18+ years of pet health expertise
  • Trusted by pet parents nationwide
  • 150K+ positive reviews
  • 18+ years of pet health expertise
  • Trusted by pet parents nationwide
  • 150K+ positive reviews
  • 18+ years of pet health expertise

How to Use

Spray affected area thoroughly and evenly until wet. Do not allow pet to lick product. Continue to supervise pet until coat and skin are completely dry. Apply twice daily for one week, then once per day for one more week. If needed, continue every other day for two additional weeks. For dogs and cats 12 weeks and over.

When to expect results

After First Use
  • Provides quick, targeted soothing for irritated skin and hot spots.
  • Easy spray application allows for mess-free, on-the-spot care.
  • Helps pets feel more comfortable right where they need it.
Within 1 Week
  • Treated areas may begin to look calmer and less red.
  • Pets may show reduced scratching, licking, or biting in problem spots.
  • Skin feels cleaner and more supported between baths.
After 2–3 Weeks
  • Consistent use helps maintain skin hydration and comfort.
  • Areas prone to hot spots or irritation look healthier and more balanced.
  • Coat surrounding treated areas begins to look softer and smoother.
Ongoing Use
  • Helps manage recurring irritation with regular application.
  • Provides a convenient way to maintain skin comfort between shampoos.
  • Supports long-term wellness as part of a complete hot spot care routine.

safe ingredients that work

Made with , , and .

The smartest way to care for your pet

Trusted & Certified

NASC Quality Seal

NASC Quality Seal

Quality standards you can trust.

GMP Certified Facility

GMP Certified Facility

Made with consistent quality practices.

Made In The USA

Made In The USA

Proudly made with care in the USA.

Vet-Backed Formulas

Vet-Backed Formulas

Guided by veterinary expertise.

4.9
Rated 4.9 out of 5 stars
Based on 105 reviews
99%would recommend this product
Slide 1 selected
105 reviews
  • MD Profile picture for Mandie D.google logo
    Mandie D.
    Verified Reviewer
    I recommend this product
    Rated 5 out of 5 stars
    2 months ago
    I love this product!!

    Finally I have found a itch relief for my Angus McGee that works almost instantly!! Ive tried almost everything out there and this was a game changer!! He is much more content and Happy. I will continue using this !! Thank you!!

  • KI
    Karlie I.
    Flag of United States
    I recommend this product
    Rated 5 out of 5 stars
    11 months ago
    LOVE the Hot Spot & Itch Relief Medicated Spray!

    This spray is great for my cat! Especially if we go outside, she may get itchy from the grass or get a flea, or anything else from being out too long. This way, I don't have to torture my cat with a bath!

  • RT
    Rayanna T.
    Flag of United States
    I recommend this product
    Rated 4 out of 5 stars
    11 months ago
    Spray

    The smell is mild. I didn’t see much change over time with use. In the moments after i sprayed the itching was subdued.

  • S
    Stephanie
    I recommend this product
    Rated 5 out of 5 stars
    11 months ago
    Works really well

    My dog gets hot spots every now and then and this stuff works really well.

  • GD
    Gabriela D.
    Flag of United States
    I recommend this product
    Rated 5 out of 5 stars
    1 year ago
    Great Itch Relief Between Baths

    I was given this product in exchange for my honest review. I’ve been using the Veterinary Formula Hot Spot & Itch Relief Medicated Spray as a between-washes treatment and it has made a noticeable difference.

    The spray was really easy to apply, but my dog was a little nervous about the sound and spray at first. I found that spraying it on gloves and wiping it on worked way better for him. The product itself gave him instant relief, though it did take a little while to fully dry.

    The scent is a bit strong when first applied, but it fades once the product sets. After using it regularly, I noticed a drop in his overall itching. This has been a helpful addition to our routine, especially when I don’t have time to do a full bath.

Trusted by Veterinarians,
Loved by Pets

These formulas are created from an integrative veterinary standpoint—every ingredient is chosen for its proven benefits, sourced with care, and combined for whole-body health.

Ronit Berdugo, DVM, CVA

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Veterinarian in purple scrubs smiling in a pet care clinic with medical supplies and colorful wall art.

Frequently Asked Questions

Still have Questions?
We are here to help!

954.525.1133
Available Monday – Friday
8am – 5pm EST
support@veterinaryformula.com
Available 7 days a week

Still have Questions?
We are here to help!

954.525.1133
Available Monday – Friday
8am – 5pm EST
support@veterinaryformula.com
Available 7 days a week

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Hot Spot & Itch Relief Medicated Spray